Optimization of self-emulsifying drug delivery system of cefuroxime axetil
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چکیده
منابع مشابه
Design, Development and In Vitro Characterization of Self Emulsifying Drug Delivery System for Irbesartan
The objectives of present investigations were to optimize concentration of oil, surfactant and cosurfactant by pseudoternary phase diagrams and to develop a stable formulation of self emulsifying drug delivery system (SEDDS) in order to enhance the dissolution rate of poorly soluble Irbesartan (IBS) by SEDDS. Pseudoternary phase diagrams were constructed to identify the self emulsifying region....
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Ibuprofen (IB) a NSAID, has poor dissolution and many gastrointestinal side effects. Self-Emulsifying drug delivery system (SEDDS) has proved its efficacy to improve the solubility and dissolution of many lipophilic drugs and improve their characteristics. The objectives of this study were to develop, optimize and characterize a IBSEDDS applying Face Centered Experimental Design (FCED). The met...
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Self emulsifying is a topic of current interest for overcoming the formulation difficulties of drugs with poor aqueous solubility. SEDDS are isotropic mixture of oil, surfactant and co-surfactant with a unique ability to form fine oil-inwater (o/w) emulsions or micro emulsions upon mild agitation in the gastrointestinal tract which present the drug in a solubilized form, and the small size of f...
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ژورنال
عنوان ژورنال: Macedonian Pharmaceutical Bulletin
سال: 2021
ISSN: 1857-8969,1409-8695
DOI: 10.33320/maced.pharm.bull.2020.66.02.007